I hold a Bachelor and Masters degree in biological sciences from the Universidad de Chile. I became interested in neuroscience already during my bachelor studies, while performing ex-vivo electrophysiology in the autonomic nervous system of mammals. During my master studies, I shifted my focus towards computational neuroscience, developing neural network models of the avian visual system. After finishing my Master thesis, I made an internship in Louisiana State University working on biophysical models of mammalian dopaminergic neurons. Currently, I’m a PhD student in the AC lab, where I perform experiments dealing with behaviour and in-vivo electrophysiology in bats.
ABOUT MY PROJECT
Neuronal responses to particular sounds depend on the context in which they are presented and on their functional relevance to the animals. I am interested in understanding how sound representation in the mammalian auditory cortex is shaped by auditory experience, particularly, how complex natural sounds alter auditory processing of upcoming information in the brain of the short-tailed bat, Carollia perspicillata. Interestingly, in addition to acoustic signals, auditory cortex neurons can integrate other sensory inputs (such as visual) that are relevant to the interpretation of sounds. I am also interested in exploring how visual context can shape auditory representations in the cortex of bats. By employing multi-array electrophysiology, I will use information from local field potentials along with spike data to study context-dependent auditory processing in the mammalian cortex as well as specializations associated to bats’ brains.
Lopez-Jury- L, Rosales FG, Palomares EG, Wetekam J, & Hechavarria JC. 2022. A neuron model with unbalanced synaptic weights explains asymmetric effects of ketamine in auditory cortex. bioRxiv doi: https://doi.org/10.1101/2022.06.12.495822. Article Accepted in PLoS Biology.
Lopez-Jury L, Garcia-Rosales F, Gonzalez-Palomares E., Kössl M, Hechavarria JC. 2021. Acoustic context modulates natural sound discrimination in auditory cortex through frequency specific adaptation. Journal of Neuroscience. JN-RM-0873-21; DOI: 10.1523/JNEUROSCI.0873-21.2021
López‐Jury L, Mannel A, García‐Rosales F, & Hechavarria JC. 2019. Modified synaptic dynamics predict neural activity patterns in an auditory field within the frontal cortex. European Journal of Neuroscience